Pills!

Pills! are a set of Loot Cards in The Binding of Isaac: Four Souls.

Effects
All pill cards have you perform a dice roll. All pill cards have 3 different effects. Most of them use a formula that goes: There are also some pills which have their 5 - 6 result be good in certain situations.
 * 1 - 2 : Positive effect
 * 3 - 4 : Positive effect
 * 5 - 6 : Negative effect

The Pills
There are multiple pill cards in the game. Some are exclusive to the Expansion Packs.

In the Base Game
Blue Pills Red Pills Yellow Pills
 * 1 - 2 : Loot 1
 * 3 - 4 : Loot 3
 * 5 - 6 : Discard 1 Loot
 * 1 - 2 : +1 Damage till the end of turn
 * 3 - 4 : +1 Health till the end of turn
 * 5 - 6 : Take 1 Damage
 * 1 - 2 : Gain 4 Coins
 * 3 - 4 : Gain 7 Coins
 * 5 - 6 : Lose 4 Coins

Kickstarter Expansion Exclusives
Purple Pills
 * 1 - 2 : Recharge all of your Items
 * 3 - 4 : +1 To All of your dice Rolls till the end of turn
 * 5 - 6 : -2 To All of your dice Rolls till the end of turn

Four Souls+ Expansion Exclusives
Black Pills White Pills Yellow Spotted Pills
 * 1 - 2 : Deal 1 Damage to a player
 * 3 - 4 : Deal 1 Damage to an active Monster
 * 5 - 6 : Take 1 Damage
 * 1 - 2 : Cancel the effect of any Loot Card being played
 * 3 - 4 : All other players discard a Loot Card
 * 5 - 6 : Nothing
 * 1 - 2 : Reroll one of your items
 * 3 - 4 : Reroll any item
 * 5 - 6 : Reroll all of your items

Strategies

 * All pill cards become a lot more useful if you have any sort of roll manipulation like Book of Belial or P.H.D.
 * The Blue or Yellow pills can be played if you don't have that much Loot or Coins to lose.
 * Purple Pills could be played to purposely raise or lower your dice roll.
 * You can activate any on hit items by rolling a 5 or 6 with the Red and Black pills.
 * Rerolling all of your items using the Yellow Spotted pills may not always be a bad option.