Azazel

Azazel is a playable character in The Binding of Isaac: Four Souls.

Strategies
You can use Lord of the Pit to get yourself out of sticky situations, when you lose a roll and are going to take damage, you can use this item to avoid that damage, you can choose to keep attacking that monster, or fight a weaker one. You can also use this on other players, when they get the killing blow on a boss, you can force them out of combat, forcing them to try again. Keep in mind that monsters only heal at the end of a turn, so you are basically forcing them to reroll a roll, this will be incredibly annoying to other players and might paint a target on your back, so it's up to you if you want that or not.

Additional notes

 * Azazel is an exclusive character in the Gold Box tier, which you could only get during the Kickstarter.